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    family income from age 6 and age 10 assessments.1 MeanPredictors Race of mother (White) Age of mother at time 1 Sex of adolescent (male) Age of adolescent Childhood family income1 Dysregulation prole (DP) at age 6 Dysregulation prole (DP) at age 10 Peer cigarette use at age 10 Depression scores at age 10 Depression scores at age 14 Authoritative parenting at age 14 Pubertal timing Pubertal Timing ?RaceTABLE 3: Final step of logistic regression model predicting recent cannabis use ( = 263). Beta 2.64 -0.17 0.41 1.23 -0.03 2.11 -2.08 -1.00 0.00 0.07 -0.56 0.93 -2.82 S.E. 0.87 0.20 0.48 0.37 0.02 0.94 1.45 0.54 0.03 0.03 0.30 0.39 0.91 Wald 9.31 0.72 0.76 11.31 1.91 4.99 2.06 3.47 0.00 5.12 3.52 5.74 j.cub.2015.05.021 9.70 Exp (B) 14.0 0.85 1.51 3.42 0.97 8.23 0.13 0.37 1.00 1.07 0.57 two.54 0.< .05, < .01. family income from age 6 and age 10 assessments.Condence intervals 2.57?6.2 0.57?.25 0.60?.83 1.67?.01 0.93?.01 1.30?2.3 0.01?.15 0.13?.05 0.95?.06 1.01?.13 0.32?.03 1.18?.44 0.01?.6 more likely to have recently used cannabis. By contrast, the African-American offspring who matured later appeared to be at greater risk of recent cannabis use than AfricanAmerican offspring who matured earlier than their peers.50 45 40 35 30 25 20 15 10 5 0 Early puberty Black offspring White offspring On timeISRN Addiction4. Discussionis was the rst study to examine DP in offspring of teenage mothers and to associate childhood DP with early cannabis use in these vulnerable adolescents. DP at age 6 was a signicant predictor of cannabis use at age 14, suggesting that it may be possible to identify children at risk of substance abuse at an early age within this vulnerable group. DP was correlated across middle childhood in this cohort, consistent with Althoff et 1940-0640-8-15 al. [4]. However, DP at age 10 didn’t predict cannabis use by age 14, contrary to our hypotheses. It’s doable that behavioral dysregulation at age 6 may possibly be in particular detrimental for behavioral danger, at age of entry in to the school technique. is is often a developmental period when children come to be independent from their families and spend their entire day at school, finding out to focus on new cognitive tasks and avoid disrupting the classroom. ey must also discover to kind and nurture peer relationships which are significantly less managed by their families though at college. Kids who fail to meet these challenges at a young age may possibly be particularly vulnerable to early cannabis use when compared with young children who only develop into particularly dysregulated by age ten. IOX2 site Having said that, there was a separate independent impact of age 6 DP on cannabis use at age 14, aer controlling for the effects of age ten peer cigarette use and age 14 depressive symptoms, indicating an additive effect of childhood DP on risk for adolescent can.